Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Inflammation
ADR ID BADD_A05823
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.05      Inflammations
08.01.05.007      Inflammation
Description A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code 10061218
MeSH ID D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Interleukin-1 alphaP01583T16340
Interleukin-10P29456Not Available
Interleukin-6P05231T32578
Interleukin-8P10145T22658
Nuclear receptor subfamily 4 group A member 3Q92570T93949
Retinol-binding protein 1P09455Not Available
Tumor necrosis factorP01375T20178
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00661Didanosine--
BADD_D00680Dimethyl fumarate0.014669%
BADD_D00684Dinoprostone--
BADD_D00698Dobutamine hydrochloride--
BADD_D00699Docetaxel0.004263%
BADD_D00704Dolutegravir sodium--
BADD_D00723Doxorubicin0.001332%
BADD_D00725Doxycycline--
BADD_D00727Doxycycline hyclate--
BADD_D00728Doxycycline monohydrate--
BADD_D00734Duloxetine--
BADD_D00736Dutasteride0.001565%
BADD_D00749Efavirenz--
BADD_D00762Elvitegravir--
BADD_D00765Empagliflozin--
BADD_D00766Emtricitabine--
BADD_D00771Enfuvirtide--
BADD_D00772Enoxaparin sodium--
BADD_D00773Entacapone0.012575%
BADD_D00786Eplerenone0.034027%
BADD_D00794Ergocalciferol0.000102%
BADD_D00800Erlotinib--
BADD_D00813Esmolol--
BADD_D00821Estradiol0.000278%
BADD_D00836Estropipate--
BADD_D00852Etonogestrel0.004537%
BADD_D00853Etophos--
BADD_D00854Etoposide--
BADD_D00857Etravirine--
BADD_D00858Everolimus0.008393%
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